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KMID : 1001920070410060408
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Journal of Korean Neurosurgical Society
2007 Volume.41 No. 6 p.408 ~ p.410
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Paradoxical Deterioration of Intramedullary Spinal Tuberculomas during Antituberculous Therapy
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Jang Keum-Jun
Jwa Cheol-Su
Kim Kang-Hyun
Kang Jae-Kyu
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Abstract
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"Paradoxical deterioration" during antituberculous therapy is generally defined as the clinical or radiological worsening of pre-existing tuberculous lesions or the development of new lesions in a patient who initially improves. The phenomenon of paradoxical deterioration in intramedullary tuberculoma of the spinal cord is rare and is a less established entity. The authors present an unusual case of paraparesis as a result of paradoxical deterioration of intramedullary tuberculoma despite adequate antituberculous therapy. Here, we review the relevant literatures and discuss its possible pathogenic mechanisms.
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KEYWORD
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Tuberculoma, Spinal cord, Antituberculous therapy
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